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TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA
Currently, the regulatory mechanisms of lipid metabolism in immune cells are not fully understood, and research faces challenges such as model limitations, the complexity of lipid metabolic pathways, difficulties in drug target development, and individual variability

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has received grant support and modest honoraria from Ionis Pharmaceuticals and grant support from uniQure, Regeneron Pharmaceuticals, Zydus Pharmaceuticals, and Kowa Research Institute