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The theoretical mechanism of a GLP-1 patch would involve delivering the active pharmaceutical ingredient through the skin (transdermally) into the systemic circulation

It is possible, as the authors imply, that there might be some other anti-inflammatory benefits that are having an outcome on cancer risk reduction. Wolff-Sagy shared that future work would involve looking at other cohort studies, expanding the demographics and timeframe of the study, and digging into the molecular mechanisms behind GLP-1 treatments

8 Endogenous glucagon-like peptide-1 (GLP-1) is a peptide secreted from intestinal L cells and neurons in the nucleus tractus solitarius of the caudal brainstem

Simple exercise can make a big difference

These genetic differences explain why some patients regain weight rapidly after stopping while others maintain results more easily

However, they are also being used off-label for weight-loss - with good results - but at a high cost of muscle loss, bone loss and permanent gastroparesis as well
