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Evidence Snapshot The STEP trials demonstrated significant weight reduction with semaglutide, with gastrointestinal side effects most prominent during dose escalation. Long-term micronutrient outcomes were not primary endpoints

In a separate double blinded placebo-controlled trial, weekly injections of Tirzepatide (15mg) in conjunction with lifestyle changes in obese patients could decrease body weight by 17.8% on average, over placebo after 72 weeks

Interestingly, GLP-1 signaling in the hippocampus has been described to play a direct and crucial role in regulating learning and memory, independent of motor, stress, or nociceptive impacts

ScienceDirect, doi:10.1016/j.jad.2013.08.017

What happens if my pharmacy gets investigated by the FDA

As a food supplement rather than a licensed medicine, berberine products are not subject to the same quality controls as prescription medications, meaning contamination, mislabelling, or inconsistent dosing may occur