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They are primarily used in the management of type 2 diabetes (T2D).

Trial registration Clinicaltrials.gov, NCT04777396 and NCT04777409

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It responds to signals, interactions, and pathways

The authors discuss the preclinical literature and emerging clinical evidence that support the rationale for investigating the use of glucagon-like peptide-1 receptor agonists to prevent and treat several neurodegenerative diseases of aging, with a focus on Alzheimers disease.