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Inactivation of TOR activates a complex containing the protein kinase Atg1 and the phosphoprotein Atg13 and this leads to the nucleation of the autophagosomal membrane via a complex that contains Atg14, Vps15 and Vps34

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10.1136/bcr-2023-254709 176 The definition (2007)

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Dosing may need to be reduced should such effects occur until a more comfortable level is reached
