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Metabolic regulation of inflammation

Studies have connected PCOS to an increased risk of both Type 2 diabetes and obesity, so it can be helpful to treat both insulin resistance and weight gain at the same time in patients with PCOS

However, its direct therapeutic application is limited by its rapid inactivation via the enzyme dipeptidyl peptidase 4 (DPP-4), which cleaves GLP-1 (736) at position 8 to generate the inactive metabolite GLP-1 (936), resulting in a plasma half-life of only 1 to 2 min

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Also known as pattern hair loss, this is a progressive hair loss condition

SPECIFIC DRUGS FOR SPECIFIC CONDITIONS The guideline authors analyzed previous clinical trial results, evaluating the impact of medications on weight loss, their safety profile, and their effectiveness in the presence of specific complications