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Code availability Custom codes generated to analyse data from the study are accessible at References Wadden, T

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Lorcaserin, a high-selective 5-HTR 2C agonist that inhibits appetite [233], could alleviate obesity and diabetes in humans [209] with cardiovascular safety [97]

If moving from retatrutide to a lower-potency medication for maintenance, the reduced appetite suppression makes it easier to consume adequate protein, which naturally supports lean tissue recovery

The interplay of glucagon-like Peptide-1 receptor trafficking and Signalling in pancreatic Beta cells

Mice globally deficient for GLP1 receptors also exhibited increased blood glucose levels in response to an intraperitoneal glucose tolerance test (ipGTT) (Scrocchi & Drucker, 1998)