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Those reports suggested a MTHFR polymorphism independent mechanism in aging and cell-type specific global DNA methylation

doi: 10.1016/j.xcrm.2022.100633 [DOI] [PMC free article] [PubMed] [Google Scholar] [411].Whitfield J, McKay AKA, Tee N, et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] 267.Sandouka S., Shekh-Ahmad T

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The analysis has demonstrated an increased representation of these taxa in the fecal samples of non-lithogenic subjects
