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The Gu group first revealed that p53 promotes ferroptosis via a novel tumor suppression mechanism that is independent of canonical p53 functions in cell-cycle arrest and senescence [61, 62]
Acknowledgements This study was supported by the National Research Foundation (NRF) Grant (grant nos
For instance, during hepatitis C virus (HCV) infection, the expression of non-structural protein 5 (NS5) in the ER contributes to Ca 2+ release and subsequent oxidative stress [56,57]
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Appl Physiol Nutr Metab 40, 343352
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