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Overall Clinical Fit: "More weight loss on average" does not automatically mean "best choice for every patient." Your doctor will consider medication tolerability, insurance coverage, existing comorbidities, and your personal medical history when deciding between the two

"To ensure the right patients are getting the most appropriate treatment, individuals with a diagnosed history of disordered eating are screened and recommended to seek in-person care rather than on Ro." Keeping the conversation grounded in health and science is the way forward, Gupta says, including "who these medications are appropriate for, how theyre used safely while also being mindful of the broader social impact." DeCaro adds it's important to remember these medications are not approved as a treatment for an eating disorder and that long-term effects of the drugs are largely unknown

Ive sent you a quick note as well, happy to connect when you have time.

Clinical trial

This is important because it separates the skin benefit from the metabolic benefit

Observational Study Design